The MiniBooNE experiment at Fermilab reports results from an analysis of the combined $ u_e$ and $bar u_e$ appearance data from $6.46 times 10^{20}$ protons on target in neutrino mode and $11.27 times 10^{20}$ protons on target in antineutrino mode. A total excess of $240.3 pm 34.5 pm 52.6$ events ($3.8 sigma$) is observed from combining the two data sets in the energy range $200<E_ u^{QE}<1250$ MeV. In a combined fit for CP-conserving $ u_mu rightarrow u_e$ and $bar{ u}_{mu}rightarrowbar{ u}_e$ oscillations via a two-neutrino model, the background-only fit has a $chi^2$-probability of 0.03% relative to the best oscillation fit. The data are consistent with neutrino oscillations in the $0.01 < Delta m^2 < 1.0$ eV$^2$ range and with the evidence for antineutrino oscillations from the Liquid Scintillator Neutrino Detector (LSND).