In the global competition, companies are propelled by an immense pressure to innovate. The trend to produce more new knowledge-intensive products or services and the rapid progress of information technologies arouse huge interest on knowledge management for innovation. However the strategy of knowledge management is not widely adopted for innovation in industries due to a lack of an effective approach of their integration. This study aims to help the designers to innovate more efficiently based on an integrated approach of knowledge management. Based on this integrated approach, a prototype of distributed knowledge management system for innovation is developed. An industrial application is presented and its initial results indicate the applicability of the approach and the prototype in practice.