The quantitative spectral analysis of low resolution Keck LRIS spectra of blue supergiants in the disk of the giant spiral galaxy M81 is used to determine stellar effective temperatures, gravities, metallicities, luminosites, interstellar reddening and a new distance using the Flux-weighted Gravity--Luminosity Relationship (FGLR). Substantial reddening and extinction is found with E(B-V) ranging between 0.13 to 0.38 mag and an average value of 0.26 mag. The distance modulus obtained after individual reddening corrections is 27.7+/-0.1 mag. The result is discussed with regard to recently measured TRGB and Cepheid distances. The metallicities (based on elements such as iron, titanium, magnesium) are supersolar (~0.2 dex) in the inner disk (R<=5kpc) and slightly subsolar (~ -0.05 dex) in the outer disk (R>10 kpc) with a shallow metallicity gradient of 0.034 dex/kpc. The comparison with published oxygen abundances of planetary nebulae and metallicities determined through fits of HST color-magnitude diagrams indicates a late metal enrichment and a flattening of the abundance gradient over the last 5 Gyrs. This might be the result of gas infall from metal rich satellite galaxies. Combining these M81 metallicities with published blue supergiant abundance studies in the Local Group and the Sculptor Group a galaxy mass metallicity-relationship based solely on stellar spectroscopic studies is presented and compared with recent studies of SDSS star forming galaxies.
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