We extend the ideas of using AdS/CFT to calculate energy loss of extended defects in strongly coupled systems to general holographic metrics. We find the equations of motion governing uniformly moving defects of various dimension and determine the corresponding energy loss rates in terms of the metric coefficients. We apply our formulae to the specific examples of both bulk geometries created by general Dp-branes, as well as to holographic superfluids. For the Dp-branes, we find that the energy loss of our defect, in addition to the expected quadratic dependence on velocity, depends on velocity only via an effective blueshifted temperature - despite the existence of a microscopic length scale in the theory. We also find, for a certain value of p and dimension of the defect, that the energy loss has no dependence on temperature or velocity other than the aforementioned quadratic dependence on velocity. For the superfluid example, we find agreement with previous results on the existence of a cutoff velocity, below which the probe experiences no drag force. For both examples we can easily extend the equations of motion and energy loss to defects of larger dimension.