We report on a topological Hall effect possibly induced by scalar spin chirality in a quasi-two- dimensional helimagnet Fe$_{1+x}$Sb. In the low-temperature region where the spins on interstitial- Fe (concentration $x=0.3$) intervening the $120^circ$ spin-ordered triangular planes tend to freeze, a non-trivial component of Hall resistivity with opposite sign of the conventional anomalous Hall term is observed under magnetic field applied perpendicular to the triangular-lattice plane. The observed unconventional Hall effect is ascribed to the scalar spin chirality arising from the heptamer spin-clusters around the interstitial-Fe sites, which can be induced by the spin modulation by the Dzyaloshinsky-Moriya interaction.