The article presents an overview of the results obtained at U-70 accelerator of IHEP to use bent crystals for beam control of high energy protons. Considerable attention is paid to practical application of crystals to create new modes of beam extraction from the accelerator to ensure experiments on high energy physics. It was shown that with the crystal deflectors the efficiency reached ~ 90% with intensity up to 10^12 protons per cycle of U-70. The results of experiments on the use of crystals to enhance the effectiveness of the absorption of the unused beam, as well as the use of crystals for collimation of beam halo are presented. Perspectives to use of bent crystals to extract low energy light ions from U-70 are also discussed.