The T2K experiment observes indications of $ u_murightarrow u_e$ appearance in data accumulated with $1.43times10^{20}$ protons on target. Six events pass all selection criteria at the far detector. In a three-flavor neutrino oscillation scenario with $|Delta m_{23}^2|=2.4times10^{-3}$ eV$^2$, $sin^2 2theta_{23}=1$ and $sin^2 2theta_{13}=0$, the expected number of such events is 1.5$pm$0.3(syst.). Under this hypothesis, the probability to observe six or more candidate events is 7$times10^{-3}$, equivalent to 2.5$sigma$ significance. At 90% C.L., the data are consistent with 0.03(0.04)$<sin^2 2theta_{13}<$ 0.28(0.34) for $delta_{rm CP}=0$ and a normal (inverted) hierarchy.
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