We simulate ultra-cold interacting Bosons in quasi-one-dimensional, incommensurate optical lattices. In the tight-binding limit, these lattices have pseudo-random on-site energies and thus can potentially lead to Anderson localization. We explore the parameter regimes that lead to Anderson localization and investigate the role of repulsive interactions, harmonic confinement and finite temperature. We find that interactions can obscure the exponential localization characteristic of Anderson localization, thus impeding the direct observation of this phenomenon when interactions are present.