In this paper we study dynamical supersymmetry breaking in absence of gravity with the matter content of the minimal supersymmetric standard model. The hidden sector of the theory is a strongly coupled gauge theory, realized in terms of microscopic variables which condensate to form mesons. The supersymmetry breaking scalar potential combines F, D terms with instanton generated interactions in the Higgs-mesons sector. We show that for a large region in parameter space the vacuum breaks in addition to supersymmetry also electroweak gauge symmetry. We furthermore present local D-brane configurations that realize these supersymmetry breaking patterns.