We show that there is a one-to-one correspondence between compact quantum subgroups of a co-amenable locally compact quantum group $mathbb{G}$ and certain left invariant C*-subalgebras of $C_0(mathbb{G})$. We also prove that every compact quantum subgroup of a co-amenable quantum group is co-amenable. Moreover, there is a one-to-one correspondence between open subgroups of an amenable locally compact group $G$ and non-zero, invariant C*-subalgebras of the group C*-algebra $C^*(G)$.