The results of data handling for E-184 experiment obtained with 70 GeV proton beam irradiation of active target with carbon, silicon and lead plates are presented. Two-prongs neutral charmed D0 and v{D}0 -mesons decays were selected. Signal / background ratio was (51+/-17) / (38+/-13). Registration efficiency for mesons was defined and evaluation for charm production cross section at threshold energy is presented: sigma(c^c) = 7.1 +/- 2.4(stat.) +/- 1.4(syst.) (mu/nucleon).