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Register a new userSecond-Order Catalytic Quasispecies Yields First-Order Phase Transition
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Added by
Emmanuel Tannenbaum
Publication date
2009
fields
Biology
and research's language is
English
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The quasispecies model describes processes related to the origin of life and viral evolutionary dynamics. We discuss how the error catastrophe that reflects the transition from localized to delocalized quasispecies population is affected by catalytic replication of different reaction orders. Specifically, we find that 2nd order mechanisms lead to 1st order discontinuous phase transitions in the viable population fraction, and conclude that the higher the interaction the lower the transition. We discuss potential implications for understanding the replication of highly mutating RNA viruses.
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