We discuss the theoretical framework to describe quasiparticle electric and heat currents in NIS tunnel junctions in the dirty limit. The approach is based on quasiclassical Keldysh-Usadel equations. We apply this theory to diffusive NISS tunnel junctions. Here N and S are respectively normal metal and superconductor reservoirs, I is an insulator layer and S is a nonequilibrium superconducting lead. We calculate the quasiparticle electric and heat currents in such structures and consider the effect of inelastic relaxation in the S lead. We find that in the absence of strong relaxation the electric current and the cooling power for voltages $eV < Delta$ are suppressed. The value of this suppression scales with the diffusive transparency parameter. We ascribe this suppression to the effect of backtunneling of nonequilibrium quasiparticles into the normal metal.