We present preliminary results on a search for squarks and gluinos in proton-antiproton collisions with a center-of-mass energy of 1.96 TeV and based on about 2.0 fb-1 of data collected by the CDF detector in the Tevatron Run II. Events with multiple jets of hadrons and large missing transverse energy in the final state are studied within the framework of minimal supergravity (mSUGRA) and assuming R-parity conservation. The results are compared to Standard Model predictions and limits on gluino and squark masses are extracted. A specific search for the supersymmetric partner of the bottom quark produced from gluino decays is carried out using a sample of events with missing transverse energy and two or more jets, at least one of them b-tagged. Good agreement is found between data and Standard Model predictions, and limits on gluino and sbottom masses are extracted.
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