A classification of D-branes in Type IIB Op^- orientifolds and orbifolds in terms of Real and equivariant KK-groups is given. We classify D-branes intersecting orientifold planes from which are recovered some special limits as the spectrum for D-branes on top of Type I Op^- orientifold and the bivariant classification of Type I D-branes. The gauge group and transformation properties of the low energy effective field theory living in the corresponding unstable D-brane system are computed by extensive use of Clifford algebras. Some speculations about the existence of oth
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