Characterising the circumstellar dust around nearby main sequence stars is a necessary step in understanding the planetary formation process and is crucial for future life-finding space missions such as ESAs Darwin or NASAs Terrestrial Planet Finder (TPF). Besides paving the technological way to Darwin/TPF, the space-based infrared interferometers Pegase and FKSI (Fourier-Kelvin Stellar Interferometer) will be valuable scientific precursors in that respect. In this paper, we investigate the performance of Pegase and FKSI for exozodiacal disc detection and compare the results with ground-based nulling interferometers. Besides their main scientific goal (characterising hot giant extrasolar planets), Pegase and FKSI are very efficient in assessing within a few minutes the level of circumstellar dust in the habitable zone around nearby main sequence stars. They are capable of detecting exozodiacal discs respectively 5 and 1 time as dense as the solar zodiacal cloud and they outperform any ground-based instrument. Unlike Pegase, FKSI can achieve this sensitivity for most targets of the Darwin/TPF catalogue thanks to an appropriate combination of baseline length and observing wavelength. The sensitivity of Pegase could, however, be significantly boosted by considering a shorter interferometric baseline length. These space-based interferometers would be complementary to Antarctica-based instruments in terms of sky coverage and would be ideal instruments for preparing future life-finding space missions.