Without resorting to spin-spin coupling, we propose a scalable spin quantum computing scheme assisted with a semiconductor multiple-quantum-dot structure. The techniques of single electron transitions and the nanostructure of quantum-dot cellular automata (QCA) are used to generate charge entangled states of two electrons, which are then converted into spin entanglement states using single-spin rotations only. Deterministic two-qubit quantum gates are also manipulated using only single-spin rotations with the help of QCA. A single-shot readout of spin states can be carried out by coupling the multiple dot structure to a quantum point contact. As a result, deterministic spin-interaction-free quantum computing can be implemented in semiconductor nanostructure.