Epigenome modulation in response to the environment potentially provides a mechanism for organisms to adapt, both within and between generations. However, neither the extent to which this occurs, nor the molecular mechanisms involved are known. Here we investigate DNA methylation variation in Swedish Arabidopsis thaliana accessions grown at two different temperatures. Environmental effects on DNA methylation were limited to transposons, where CHH methylation was found to increase with temperature. Genome-wide association mapping revealed that the extensive CHH methylation variation was strongly associated with genetic variants in both cis and trans, including a major trans-association close to the DNA methyltransferase CMT2. Unlike CHH methylation, CpG gene body methylation (GBM) on the coding region of genes was not affected by growth temperature, but was instead strongly correlated with the latitude of origin. Accessions from colder regions had higher levels of GBM for a significant fraction of the genome, and this was correlated with elevated transcription levels for the genes affected. Genome-wide association mapping revealed that this effect was largely due to trans-acting loci, a significant fraction of which showed evidence of local adaptation. These findings constitute the first direct link between DNA methylation and adaptation to the environment, and provide a basis for further dissecting how environmentally driven and genetically determined epigenetic variation interact and influence organismal fitness.
Expectation values of the Breit operators and the $Q$ terms are calculated for HD$^+$ with the vibrational number $v=0-4$ and the total angular momentum $L=0-4$. Relativistic and radiative corrections to some ro-vibrational transition frequencies are determined. Numerical uncertainty in $R_{infty}alpha^2$ order correction is reduced to sub kHz or smaller. Our work provides an independent verification of Korobovs calculations [Phys. Rev. A {bf74}, 052506 (2006); {bf77}, 022509 (2008)].
Influence of hole shape on extraordinary optical transmission was investigated using hole arrays consisting of rectangular holes with different aspect ratio. It was found that the transmission could be tuned continuously by rotating the hole array. Further more, a phase was generated in this process, and linear polarization states could be changed to elliptical polarization states. This phase was correlated with the aspect ratio of the holes. An intuitional model was presented to explain these results.
Discrimination of unitary operations is a fundamental quantum information processing task. Assisted with linear optical elements, we experimentally demonstrate perfect discrimination between single-bit unitary operations using two methods--sequential scheme and parallel scheme. The complexity and resource consumed in these two schemes are analyzed and compared.
