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We consider the estimation of densities in multiple subpopulations, where the available sample size in each subpopulation greatly varies. This problem occurs in epidemiology, for example, where different diseases may share similar pathogenic mechanism but differ in their prevalence. Without specifying a parametric form, our proposed method pools information from the population and estimate the density in each subpopulation in a data-driven fashion. Drawing from functional data analysis, low-dimensional approximating density families in the form of exponential families are constructed from the principal modes of variation in the log-densities. Subpopulation densities are subsequently fitted in the approximating families based on likelihood principles and shrinkage. The approximating families increase in their flexibility as the number of components increases and can approximate arbitrary infinite-dimensional densities. We also derive convergence results of the density estimates with discrete observations. The proposed methods are shown to be interpretable and efficient in simulation as well as applications to electronic medical record and rainfall data.
The simultaneous estimation of many parameters $eta_i$, based on a corresponding set of observations $x_i$, for $i=1,ldots, n$, is a key research problem that has received renewed attention in the high-dimensional setting. %The classic example involv
Conditional density estimation generalizes regression by modeling a full density f(yjx) rather than only the expected value E(yjx). This is important for many tasks, including handling multi-modality and generating prediction intervals. Though fundam
We propose a new method for changepoint estimation in partially-observed, high-dimensional time series that undergo a simultaneous change in mean in a sparse subset of coordinates. Our first methodological contribution is to introduce a MissCUSUM tra
We introduce a new nonparametric density estimator inspired by Markov Chains, and generalizing the well-known Kernel Density Estimator (KDE). Our estimator presents several benefits with respect to the usual ones and can be used straightforwardly as
We consider the nonparametric estimation of an S-shaped regression function. The least squares estimator provides a very natural, tuning-free approach, but results in a non-convex optimisation problem, since the inflection point is unknown. We show t