We study the physics with finite nuclear density in the framework of AdS/QCD with holographic baryon field included. Based on a mean field type approach, we introduce the nucleon density as a bi-fermion condensate of the lowest mode of the baryon field and calculate the density dependence of the chiral condensate and the nucleon mass. We observe that the chiral condensate as well as the mass of nucleon decrease with increasing nuclear density. We also consider the mass splitting of charged vector mesons in iso-spin asymmetric nuclear matter.
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