We propose a hybrid quantum computing scheme where qubit degrees of freedom for computation are combined with quantum continuous variables for communication. In particular, universal two-qubit gates can be implemented deterministically through qubit-qubit communication, mediated by a continuous-variable bus mode (qubus), without direct interaction between the qubits and without any measurement of the qubus. The key ingredients are controlled rotations of the qubus and unconditional qubus displacements. The controlled rotations are realizable through typical atom-light interactions in quantum optics. For such interactions, our scheme is universal and works in any regime, including the limits of weak and strong nonlinearities.