We present a search for the decays B+ -> mu+ nu_mu and B+ -> e+ nu_e in a 253 fb-1 data sample collected at the Upsilon(4S) resonance with the Belle detector at the KEKB asymmetric-energy B factory. We find no significant evidence for a signal and set 90% confidence level upper limits of B(B+ -> mu+ nu_mu) < 1.7 x 10^{-6} and B(B+ -> e+ nu_e) < 9.8 x 10^{-7}.
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