We discuss the recent progress in the study of semileptonic kaon and pion decays, including new experimental results, improved electroweak radiative corrections, form factor calculations and isospin-breaking effects. As a result, we obtain $|V_{us}|=0.22309(40)(39)(3)$ from kaon semileptonic decays and $|V_{us}/V_{ud}|=0.22908(66)(41)(40)(2)(1)$ from the ratio between the kaon and pion semileptonic decay rates. We report an apparent violation of the top-row Cabibbo-Kobayashi-Maskawa matrix unitarity at a $3.2sim 5.6sigma$ level, and a discrepancy at a $2.2sigma$ level between the value of $|V_{us}/V_{ud}|$ determined from the vector and axial charged weak interactions. Prospects for future improvements in those comparative precision tests involving $|V_{ud}|$, $|V_{us}|$ and their implications for physics beyond the Standard Model are described.