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Optical phase contains key information for biomedical and astronomical imaging. However, it is often obscured by layers of heterogeneous and scattering media, which render optical phase imaging at different depths an utmost challenge. Limited by the memory effect, current methods for phase imaging in strong scattering media are inapplicable to retrieving phases at different depths. To address this challenge, we developed a speckle three-dimensional reconstruction network (STRN) to recognize phase objects behind scattering media, which circumvents the limitations of memory effect. From the single-shot, reference-free and scanning-free speckle pattern input, STRN distinguishes depth-resolving quantitative phase information with high fidelity. Our results promise broad applications in biomedical tomography and endoscopy.
Detection of phase variations across optically transparent samples is often a difficult task. We propose and demonstrate a compact, lightweight and low cost quantitative phase contrast imager. Light diffracted from a pinhole is incident on a thick ob
CT imaging is crucial for diagnosis, assessment and staging COVID-19 infection. Follow-up scans every 3-5 days are often recommended for disease progression. It has been reported that bilateral and peripheral ground glass opacification (GGO) with or
Wavefront sensing and reconstruction are widely used for adaptive optics, aberration correction, and high-resolution optical phase imaging. Traditionally, interference and/or microlens arrays are used to convert the optical phase into intensity varia
This work focuses on the generation of far-field super-resolved pure-azimuthal focal field based on the fast Fourier transform. A self-designed differential filter is first pioneered to robustly reconfigure a doughnut-shaped azimuthal focal field int
Quantitative analysis of cell structures is essential for biomedical and pharmaceutical research. The standard imaging approach relies on fluorescence microscopy, where cell structures of interest are labeled by chemical staining techniques. However,