Entangled systems in experiments may be lost or offline in distributed quantum information processing. This inspires a general problem to characterize quantum operations which result in breaking of entanglement or not. Our goal in this work is to solve this problem both in single entanglement and network scenarios. We firstly propose a local model for characterizing all entangled states that are breaking for losing particles. This implies a simple criterion for witnessing single entanglement such as generalized GHZ states and Dicke states. It further provides an efficient witness for characterizing entangled quantum networks depending mainly on the connectivity of network configurations such as $k$-independent quantum networks, completely connected quantum networks, and $k$-connected quantum networks. These networks are universal resources for measurement-based quantum computations. The strong nonlocality can be finally verified by using nonlinear inequalities. These results show distinctive features of both single entangled systems and entangled quantum networks.
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