Quantum computers built with superconducting artificial atoms already stretch the limits of their classical counterparts. While the lowest energy states of these artificial atoms serve as the qubit basis, the higher levels are responsible for both a host of attractive gate schemes as well as generating undesired interactions. In particular, when coupling these atoms to generate entanglement, the higher levels cause shifts in the computational levels that leads to unwanted $ZZ$ quantum crosstalk. Here, we present a novel technique to manipulate the energy levels and mitigate this crosstalk via a simultaneous AC Stark effect on coupled qubits. This breaks a fundamental deadlock between qubit-qubit coupling and crosstalk, leading to a 90ns CNOT with a gate error of (0.19 $pm$ 0.02) $%$ and the demonstration of a novel CZ gate with fixed-coupling single-junction transmon qubits. Furthermore, we show a definitive improvement in circuit performance with crosstalk cancellation over seven qubits, demonstrating the scalability of the technique. This work paves the way for superconducting hardware with faster gates and greatly improved multi-qubit circuit fidelities.