We present a parameter retrieval method which combines ptychography and additional prior knowledge about the object. The proposed method is applied to two applications: (1) parameter retrieval of small particles from Fourier ptychographic dark field measurements; (2) parameter retrieval of retangule with real-space ptychography. The influence of Poisson noise is discussed in the second part of the paper. The Cram{e}r Rao Lower Bound in both two applications is computed and Monte Carlo analysis is used to verify the calculated lower bound. With the computation results we report the lower bound for various noise levels and the correlation of particles in Application 1. For Application 2 the correlation of parameters of the rectangule is discussed.