The fundamental changes in power supply and increasing decentralization require more active grid operation and an increased integration of ICT at all power system actors. This trend raises complexity and increasingly leads to interactions between primary grid operation and ICT as well as different power system actors. For example, virtual power plants control various assets in the distribution grid via ICT to jointly market existing flexibilities. Failures of ICT or targeted attacks can thus have serious effects on security of supply and system stability. This paper presents a holistic approach to providing methods specifically for actors in the power system for prevention, detection, and reaction to ICT attacks and failures. The focus of our measures are solutions for ICT monitoring, systems for the detection of ICT attacks and intrusions in the process network, and the provision of actionable guidelines as well as a practice environment for the response to potential ICT security incidents.