The relative average minimum projected separations of star clusters in the Legacy ExtraGalactic UV Survey (LEGUS) and in tidal dwarfs around the interacting galaxy NGC 5291 are determined as a function of cluster mass to look for cluster-cluster mass segregation. Class 2 and 3 LEGUS clusters, which have a more irregular internal structure than the compact and symmetric class 1 clusters, are found to be mass segregated in low mass galaxies, which means that the more massive clusters are systematically bunched together compared to the lower mass clusters. This mass segregation is not present in high-mass galaxies nor for class 1 clusters. We consider possible causes for this segregation including differences in cluster formation and scattering in the shallow gravitational potentials of low mass galaxies.