If a grand-unified extension of the asymptotically safe Reuter fixed-point for quantum gravity exists, it determines free parameters of the grand-unified scalar potential. All quartic couplings take their fixed-point values in the trans-Planckian regime. They are irrelevant parameters that are, in principle, computable for a given particle content of the grand unified model. In turn, the direction of spontaneous breaking of the grand-unified gauge symmetry becomes predictable. For the flow of the couplings below the Planck mass, gauge and Yukawa interactions compete for the determination of the minimum of the effective potential.