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We consider a one-dimensional elastic membrane, which is pushed by growing filaments. The filaments tend to grow by creating local protrusions in the membrane and this process has surface energy and bending energy costs. Although it is expected that with increasing surface tension and bending rigidity, it should become more difficult to create a protrusion, we find that for a fixed bending rigidity, as the surface tension increases, protrusions are more easily formed. This effect also gives rise to nontrivial dependence of membrane velocity on the surface tension, characterized by a dip and a peak. We explain this unusual phenomenon by studying in detail the interplay of the surface and the bending energy and show that this interplay is responsible for a qualitative shape change of the membrane, which gives rise to the above effect.
We study the force generation by a set of parallel actin filaments growing against an elastic membrane. The elastic membrane tries to stay flat and any deformation from this flat state, either caused by thermal fluctuations or due to protrusive polym
Gaining access to the cell interior is fundamental for many applications, such as electrical recording, drug and biomolecular delivery. A very promising technique consists of culturing cells on nano/micro pillars. The tight adhesion and high local de
We compute the absolute Poissons ratio $ u$ and the bending rigidity exponent $eta$ of a free-standing two-dimensional crystalline membrane embedded into a space of large dimensionality $d = 2 + d_c$, $d_c gg 1$. We demonstrate that, in the regime of
Bacterial processes ranging from gene expression to motility and biofilm formation are constantly challenged by internal and external noise. While the importance of stochastic fluctuations has been appreciated for chemotaxis, it is currently believed
We investigate the mechanical interplay between the spatial organization of the actin cytoskeleton and the shape of animal cells adhering on micropillar arrays. Using a combination of analytical work, computer simulations and in vitro experiments, we