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We investigate methods for learning partial differential equation (PDE) models from spatiotemporal data under biologically realistic levels and forms of noise. Recent progress in learning PDEs from data have used sparse regression to select candidate terms from a denoised set of data, including approximated partial derivatives. We analyze the performance in utilizing previous methods to denoise data for the task of discovering the governing system of partial differential equations (PDEs). We also develop a novel methodology that uses artificial neural networks (ANNs) to denoise data and approximate partial derivatives. We test the methodology on three PDE models for biological transport, i.e., the advection-diffusion, classical Fisher-KPP, and nonlinear Fisher-KPP equations. We show that the ANN methodology outperforms previous denoising methods, including finite differences and polynomial regression splines, in the ability to accurately approximate partial derivatives and learn the correct PDE model.
We develop a framework for estimating unknown partial differential equations from noisy data, using a deep learning approach. Given noisy samples of a solution to an unknown PDE, our method interpolates the samples using a neural network, and extract
Machine learning of partial differential equations from data is a potential breakthrough to solve the lack of physical equations in complex dynamic systems, but because numerical differentiation is ill-posed to noise data, noise has become the bigges
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We describe a neural-based method for generating exact or approximate solutions to differential equations in the form of mathematical expressions. Unlike other neural methods, our system returns symbolic expressions that can be interpreted directly.