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The article considers the problem of estimating a high-dimensional sparse parameter in the presence of side information that encodes the sparsity structure. We develop a general framework that involves first using an auxiliary sequence to capture the side information, and then incorporating the auxiliary sequence in inference to reduce the estimation risk. The proposed method, which carries out adaptive SURE-thresholding using side information (ASUS), is shown to have robust performance and enjoy optimality properties. We develop new theories to characterize regimes in which ASUS far outperforms competitive shrinkage estimators, and establish precise conditions under which ASUS is asymptotically optimal. Simulation studies are conducted to show that ASUS substantially improves the performance of existing methods in many settings. The methodology is applied for analysis of data from single cell virology studies and microarray time course experiments.
Adaptive multiple testing with covariates is an important research direction that has gained major attention in recent years. It has been widely recognized that leveraging side information provided by auxiliary covariates can improve the power of fal
Estimation of a precision matrix (i.e., inverse covariance matrix) is widely used to exploit conditional independence among continuous variables. The influence of abnormal observations is exacerbated in a high dimensional setting as the dimensionalit
One central goal of design of observational studies is to embed non-experimental data into an approximate randomized controlled trial using statistical matching. Researchers then make the randomization assumption in their downstream, outcome analysis
In this paper, we consider the distributed mean estimation problem where the server has access to some side information, e.g., its local computed mean estimation or the received information sent by the distributed clients at the previous iterations.
A great challenge to steganography has arisen with the wide application of steganalysis methods based on convolutional neural networks (CNNs). To this end, embedding cost learning frameworks based on generative adversarial networks (GANs) have been p