We report on the discovery of a dramatic X-ray spectral variability event observed in a $zsim 1$ broad line type-1 QSO. The XMM-Newton spectrum from the year 2000 is characterized by an unobscured power-law spectrum with photon index of $Gammasim 2$, a column density of $N_{mathrm{H}}sim 5times 10^{20},mathrm{cm^{-2}}$, and no prominent reflection component. Five years later, Chandra captured the source in a heavily-obscured, reflection-dominated state. The observed X-ray spectral variability could be caused by a Compton-thick cloud with $N_{mathrm{H}}sim 2times 10^{24},mathrm{cm^{-2}}$ eclipsing the direct emission of the hot corona, implying an extreme $N_{mathrm{H}}$ variation never before observed in a type-1 QSO. An alternative scenario is a corona that switched off in between the observations. In addition, both explanations require a significant change of the X-ray luminosity prior to the obscuration or fading of the corona and/or a change of the relative geometry of the source/reflector system. Dramatic X-ray spectral variability of this kind could be quite common in type-1 QSOs, considering the relatively few datasets in which such an event could have been identified. Our analysis implies that there may be a population of type-1 QSOs which are Compton-thick in the X-rays when observed at any given time.