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This paper introduces a novel technique to estimate tissue displacement in quasi-static elastography. A major challenge in elastography is estimation of displacement (also referred to time-delay estimation) between pre-compressed and post-compressed ultrasound data. Maximizing normalized cross correlation (NCC) of ultrasound radio-frequency (RF) data of the pre- and post-compressed images is a popular technique for strain estimation due to its simplicity and computational efficiency. Several papers have been published to increase the accuracy and quality of displacement estimation based on NCC. All of these methods use spatial windows to estimate NCC, wherein displacement magnitude is assumed to be constant within each window. In this work, we extend this assumption along the temporal domain to exploit neighboring samples in both spatial and temporal directions. This is important since traditional and ultrafast ultrasound machines are, respectively, capable of imaging at more than 30 frame per second (fps) and 1000 fps. We call our method spatial temporal normalized cross correlation (STNCC) and show that it substantially outperforms NCC using simulation, phantom and in-vivo experiments.
Ultrasound elastography is an emerging noninvasive imaging technique wherein pathological alterations can be visualized by revealing the mechanical properties of the tissue. Estimating tissue displacement in all directions is required to accurately e
In this paper, we propose Plane Wave Elastography (PWE), a novel ultrasound shear wave elastography (SWE) approach. Currently, commercial methods for SWE rely on directional filtering based on the prior knowledge of the wave propagation direction, to
Objective: Realistic tissue-mimicking phantoms are essential for the development, the investigation and the calibration of medical imaging techniques and protocols. Because it requires taking both mechanical and imaging properties into account, the d
We present an adaptation of the pixel-reassignment technique from confocal fluorescent microscopy to coherent ultrasound imaging. The method, Ultrasound Pixel-Reassignment (UPR), provides a resolution and signal to noise (SNR) improvement in ultrasou
In this paper, we consider the problem of estimating the internal displacement field of an object which is being subjected to a deformation, from Optical Coherence Tomography (OCT) images before and after compression. For the estimation of the intern