DM-Ice is a phased experimental program using low-background NaI(Tl) crystals with the aim to unambiguously test the claim of dark matter detection by the DAMA experiments. DM-Ice17, consisting of 17 kg of NaI(Tl), has been continuously operating at a depth of 2457 m in the South Pole ice for over five years, demonstrating the feasibility of a low-background experiment in the Antarctic ice. Studies of low and high energy spectra, an annual modulation analysis, and a WIMP exclusion limit based on the physics run of DM-Ice17 are presented. We also discuss the plan and projected sensitivity of a new joint physics run, COSINE-100, with upgraded detectors at the Yangyang Underground Laboratory in Korea.