We study the two-flavor Nambu--Jona-Lasinio model with the Polyakov loop (PNJL model) in the presence of a strong magnetic field and a chiral chemical potential $mu_5$ which mimics the effect of imbalanced chirality due to QCD instanton and/or sphaleron transitions. Firstly we focus on the properties of chiral symmetry breaking and deconfinement crossover under the strong magnetic field. Then we discuss the role of $mu_5$ on the phase structure. Finally the chirality charge, electric current, and their susceptibility, which are relevant to the Chiral Magnetic Effect, are computed in the model.