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We present a calculation of the B and D meson decay constants in lattice QCD with two (Nf=2) flavours of light dynamical quarks, using an O(a)-improved Wilson action for both light and heavy quarks and a renormalization-group improved gauge action. Simulations are made at three values of lattice spacing a=0.22, 0.16, 0.11 fm and four values of sea quark mass in the range m_PS/m_V ~= 0.8-0.6. Our estimate for the continuum values of the decay constants are fBd = 208(10)(11) MeV, fBs = 250(10)(13)(^{+8}_{-0}) MeV, fDd = 225(14)(14) MeV, fDs = 267(13)(17)(^{+10}_{-0}) MeV for Nf=2 where the statistical and systematic errors are separately listed, and the third error for fBs and fDs show uncertainty of determination of strange quark mass. We also carry out a set of quenched simulations using the same action to make a direct examination of sea quark effects. Taking the ratio of results for Nf=2 and Nf=0, we obtain fb^{Nf=2}/fb^{Nf=0} = 1.11(6), fbs^{Nf=2}/fbs^{Nf=0} = 1.14(5), fd^{Nf=2}/fd^{Nf=0} = 1.03(6), fds^{Nf=2}/fds^{Nf=0} = 1.07(5). They show a 10-15% increase in the Nf=2 results over those of Nf=0 for the B meson decay constants, while evidence for such a trend is statistically less clear for the D meson decay constants.
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