Dust measurements in the outer solar system are reviewed. Only the plasma wave instrument on board Voyagers 1 and 2 recorded impacts in the Edgeworth-Kuiper belt (EKB). Pioneers 10 and 11 measured a constant dust flux of 10-micron-sized particles out to 20 AU. Dust detectors on board Ulysses and Galileo uniquely identified micron-sized interstellar grains passing through the planetary system. Impacts of interstellar dust grains onto big EKB objects generate at least about a ton per second of micron-sized secondaries that are dispersed by Poynting-Robertson effect and Lorentz force. We conclude that impacts of interstellar particles are also responsible for the loss of dust grains at the inner edge of the EKB. While new dust measurements in the EKB are in an early planning stage, several missions (Cassini and STARDUST) are en route to analyze interstellar dust in much more detail.