In this paper I summarize the science motivations, as well as a few mid-infrared spectroscopic methods used to identify the principal mechanisms of energy production in dust enshrouded galactic nuclei. The development of the various techniques is briefly discussed. Emphasis is given to the use of the data which are becoming available with the infrared spectrograph (IRS) on Spitzer, as well as the results which have been obtained by IRS over the past two years.