The annotation of domain experts is important for some medical applications where the objective groundtruth is ambiguous to define, e.g., the rehabilitation for some chronic diseases, and the prescreening of some musculoskeletal abnormalities without further medical examinations. However, improper uses of the annotations may hinder developing reliable models. On one hand, forcing the use of a single groundtruth generated from multiple annotations is less informative for the modeling. On the other hand, feeding the model with all the annotations without proper regularization is noisy given existing disagreements. For such issues, we propose a novel agreement learning framework to tackle the challenge of learning from multiple annotators without objective groundtruth. The framework has two streams, with one stream fitting with the multiple annotators and the other stream learning agreement information between the annotators. In particular, the agreement learning stream produces regularization information to the classifier stream, tuning its decision to be better in line with the agreement between the annotators. The proposed method can be easily plugged to existing backbones developed with majority-voted groundtruth or multiple annotations. Thereon, experiments on two medical datasets demonstrate improved agreement levels with annotators.
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