We give a sufficient condition for non-existence of global nonnegative mild solutions of the Cauchy problem for the semilinear heat equation $u = Lu + f(u)$ in $L^p(X,m)$ for $p in [1,infty)$, where $(X,m)$ is a $sigma$-finite measure space, $L$ is the infinitesimal generator of a sub-Markovian strongly continuous semigroup of bounded linear operators in $L^p(X,m)$, and $f$ is a strictly increasing, convex, continuous function on $[0,infty)$ with $f(0) = 0$ and $int_1^infty 1/f < infty$. Since we make no further assumptions on the behaviour of the diffusion, our main result can be seen as being about the competition between the diffusion represented by $L$ and the reaction represented by $f$ in a general setting. We apply our result to Laplacians on manifolds, graphs, and, more generally, metric measure spaces with a heat kernel. In the process, we recover and extend some older as well as recent results in a unified framework.
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