T2-Shuffling reconstructs multiple sharp T2-weighted images from a single volumetric fast spin-echo (3D-FSE) scan. Wave-CAIPI is a parallel imaging technique that achieves good reconstruction at high accelerations through additional sinusoidal gradients that induce a voxel spreading effect in the readout direction to better take advantage of coil-sensitivity information. In this work, the Shuffling model in T2-Shuffling is augmented with wave-encoding to achieve higher acceleration capability. The resulting Wave-Shuffling approach is applied to 3D-FSE and Magnetization-Prepared Rapid Gradient-Echo (MPRAGE) to achieve rapid, 1 mm-isotropic resolution, time-resolved structural imaging.
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