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Accurate retinal vessel segmentation is a challenging problem in color fundus image analysis. An automatic retinal vessel segmentation system can effectively facilitate clinical diagnosis and ophthalmological research. Technically, this problem suffers from various degrees of vessel thickness, perception of details, and contextual feature fusion. For addressing these challenges, a deep learning based method has been proposed and several customized modules have been integrated into the well-known encoder-decoder architecture U-net, which is mainly employed in medical image segmentation. Structurally, cascaded dilated convolutional modules have been integrated into the intermediate layers, for obtaining larger receptive field and generating denser encoded feature maps. Also, the advantages of the pyramid module with spatial continuity have been taken, for multi-thickness perception, detail refinement, and contextual feature fusion. Additionally, the effectiveness of different normalization approaches has been discussed in network training for different datasets with specific properties. Experimentally, sufficient comparative experiments have been enforced on three retinal vessel segmentation datasets, DRIVE, CHASEDB1, and the unhealthy dataset STARE. As a result, the proposed method outperforms the work of predecessors and achieves state-of-the-art performance in Sensitivity/Recall, F1-score and MCC.
Retinal blood vessel can assist doctors in diagnosis of eye-related diseases such as diabetes and hypertension, and its segmentation is particularly important for automatic retinal image analysis. However, it is challenging to segment these vessels s
Retinal artery/vein (A/V) classification plays a critical role in the clinical biomarker study of how various systemic and cardiovascular diseases affect the retinal vessels. Conventional methods of automated A/V classification are generally complica
3D to 2D retinal vessel segmentation is a challenging problem in Optical Coherence Tomography Angiography (OCTA) images. Accurate retinal vessel segmentation is important for the diagnosis and prevention of ophthalmic diseases. However, making full u
Retinal fundus images are widely used for the clinical screening and diagnosis of eye diseases. However, fundus images captured by operators with various levels of experience have a large variation in quality. Low-quality fundus images increase uncer
The precise detection of blood vessels in retinal images is crucial to the early diagnosis of the retinal vascular diseases, e.g., diabetic, hypertensive and solar retinopathies. Existing works often fail in predicting the abnormal areas, e.g, sudden