Faraday rotation provides a valuable tracer of magnetic fields in the interstellar medium; catalogs of Faraday rotation measures provide key observations for studies of the Galactic magnetic field. We present a new catalog of rotation measures derived from the Canadian Galactic Plane Survey, covering a large region of the Galactic plane spanning 52 deg < l < 192 deg, -3 deg < b < 5 deg, along with northern and southern latitude extensions around l ~ 105 deg. We have derived rotation measures for 2234 sources (4 of which are known pulsars), 75% of which have no previous measurements, over an area of approximately 1300 square degrees. These new rotation measures increase the measurement density for this region of the Galactic plane by a factor of two.