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This survey paper focuses on modulation aspects of molecular communication, an emerging field focused on building biologically-inspired systems that embed data within chemical signals. The primary challenges in designing these systems are how to encode and modulate information onto chemical signals, and how to design a receiver that can detect and decode the information from the corrupted chemical signal observed at the destination. In this paper, we focus on modulation design for molecular communication via diffusion systems. In these systems, chemical signals are transported using diffusion, possibly assisted by flow, from the transmitter to the receiver. This tutorial presents recent advancements in modulation and demodulation schemes for molecular communication via diffusion. We compare five different modulation types: concentration-based, type-based, timing-based, spatial, and higher-order modulation techniques. The end-to-end system designs for each modulation scheme are presented. In addition, the key metrics used in the literature to evaluate the performance of these techniques are also presented. Finally, we provide a numerical bit error rate comparison of prominent modulation techniques using analytical models. We close the tutorial with a discussion of key open issues and future research directions for design of molecular communication via diffusion systems.
Molecular communication is a new field of communication where molecules are used to transfer information. Among the proposed methods, molecular communication via diffusion (MCvD) is particularly effective. One of the main challenges in MCvD is the in
Molecular communication between biological entities is a new paradigm in communications. Recently, we studied molecular communication between two nodes formed from synthetic bacteria. Due to high randomness in behavior of bacteria, we used a populati
Molecular communication via diffusion (MCvD) is a molecular communication method that utilizes the free diffusion of carrier molecules to transfer information at the nano-scale. Due to the random propagation of carrier molecules, inter-symbol interfe
This paper studies spatial diversity techniques applied to multiple-input multiple-output (MIMO) diffusion-based molecular communications (DBMC). Two types of spatial coding techniques, namely Alamouti-type coding and repetition MIMO coding are sugge
In this paper, we address the symbol synchronization issue in molecular communication via diffusion (MCvD). Symbol synchronization among chemical sensors and nanomachines is one of the critical challenges to manage complex tasks in the nanonetworks w