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With the increasing amounts of high-dimensional heterogeneous data to be processed, multi-modality feature selection has become an important research direction in medical image analysis. Traditional methods usually depict the data structure using fixed and predefined similarity matrix for each modality separately, without considering the potential relationship structure across different modalities. In this paper, we propose a novel multi-modality feature selection method, which performs feature selection and local similarity learning simultaniously. Specially, a similarity matrix is learned by jointly considering different imaging modalities. And at the same time, feature selection is conducted by imposing sparse l_{2, 1} norm constraint. The effectiveness of our proposed joint learning method can be well demonstrated by the experimental results on Alzheimers Disease Neuroimaging Initiative (ADNI) dataset, which outperforms existing the state-of-the-art multi-modality approaches.
We propose to apply a 2D CNN architecture to 3D MRI image Alzheimers disease classification. Training a 3D convolutional neural network (CNN) is time-consuming and computationally expensive. We make use of approximate rank pooling to transform the 3D
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Alzheimers disease (AD) is the most prevalent form of dementia. Traditional methods cannot achieve efficient and accurate diagnosis of AD. In this paper, we introduce a novel method based on dynamic functional connectivity (dFC) that can effectively