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Both image registration and label fusion in the multi-atlas segmentation (MAS) rely on the intensity similarity between target and atlas images. However, such similarity can be problematic when target and atlas images are acquired using different imaging protocols. High-level structure information can provide reliable similarity measurement for cross-modality images when cooperating with deep neural networks (DNNs). This work presents a new MAS framework for cross-modality images, where both image registration and label fusion are achieved by DNNs. For image registration, we propose a consistent registration network, which can jointly estimate forward and backward dense displacement fields (DDFs). Additionally, an invertible constraint is employed in the network to reduce the correspondence ambiguity of the estimated DDFs. For label fusion, we adapt a few-shot learning network to measure the similarity of atlas and target patches. Moreover, the network can be seamlessly integrated into the patch-based label fusion. The proposed framework is evaluated on the MM-WHS dataset of MICCAI 2017. Results show that the framework is effective in both cross-modality registration and segmentation.
Objective: A new image instance segmentation method is proposed to segment individual glands (instances) in colon histology images. This process is challenging since the glands not only need to be segmented from a complex background, they must also b
The findings of splenomegaly, abnormal enlargement of the spleen, is a non-invasive clinical biomarker for liver and spleen disease. Automated segmentation methods are essential to efficiently quantify splenomegaly from clinically acquired abdominal
Weakly supervised learning has emerged as an appealing alternative to alleviate the need for large labeled datasets in semantic segmentation. Most current approaches exploit class activation maps (CAMs), which can be generated from image-level annota
We use a well-known deep neural network framework, called Mask R-CNN, for identification of solar filaments in full-disk H-alpha images from Big Bear Solar Observatory (BBSO). The image data, collected from BBSOs archive, are integrated with the spat
Segmentation of white matter lesions and deep grey matter structures is an important task in the quantification of magnetic resonance imaging in multiple sclerosis. In this paper we explore segmentation solutions based on convolutional neural network