A previous signal processing algorithm that aimed to enhance spectral changes (SCE) over time showed benefit for hearing-impaired (HI) listeners to recognize speech in background noise. In this work, the previous SCE was manipulated to perform on target-dominant segments, rather than treating all frames equally. Instantaneous signal-to-noise ratios (SNRs) were calculated to determine whether the segments should be processed. Initially, the ideal SNR calculated by the knowledge of premixed signals was introduced to the previous SCE algorithm (SCE-iSNR). Speech intelligibility (SI) and clarity preference were measured for 12 HI listeners in steady speech-spectrum noise (SSN) and six-talk speech (STS) maskers, respectively. The results showed the SCE-iSNR algorithm improved SI significantly for both maskers at high signal-to-masker ratios (SMRs) and for STS masker at low SMRs, while processing effect on speech quality was small. Secondly, the estimated SNR obtained from real mixtures was used, resulting in another SCE-eSNR. SI and subjective rating on naturalness and speech quality were tested for 7 HI subjects. The SCE-eSNR algorithm showed improved SI for SSN masker at high SMRs and for STS masker at low SMRs, as well as better naturalness and speech quality for STS masker. The limitations of applying the algorithms are discussed.