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تسجيل مستخدم جديدSteady State Cargo Transport Modalities of Molecular Motor Ensembles Emerge from Single Motor Behavior
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Transport of intracellular cargo is often mediated by teams of molecular motors that function in a chaotic environment and varying conditions. We show that the motors have unique steady state behavior which enables transport modalities that are robust. Under reduced ATP concentrations, multi-motor configurations are preferred over single motors. Higher load force drives motors to cluster, but very high loads compel them to separate in a manner that promotes immediate cargo movement once the load reduces. These inferences, backed by analytical guarantees, provide unique insights into the coordination strategies adopted by motors.
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